HHAL
MEDICAL NEWS APRIL08
Coronary Calcium Strong Predictor of CHD Across Ethnic Groups
Central Obesity in Midlife Increases Dementia
RiskRelationship independent of body mass index
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=505918&contextCategoryId=40131
Fish Oil Has Anti-Arrhythmic
Effects in High-Risk Patients
Reduces risk in coronary artery disease patients at risk of sudden
cardiac death
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=505540&contextCategoryId=40130
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T10-4RKDHTB-6&_user=10&_coverDate=03%2F15%2F2008&_rdoc=5&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%234876%232008%23998989993%23682455%23FLA%23display%23Volume)&_cdi=4876&_sort=d&_docanchor=&_ct=34&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=cc2213be595b3a1ac99fd26358f8c991
Chronic caffeine ingestion appears to protect against disruptions in the blood brain barrier caused by a cholesterol-enriched
diet in rabbits, suggesting that caffeine might be useful in Alzheimer's disease and other disorders characterized by breakdown
of the blood brain barrier, according to research published April 3 in the Journal of Neuroinflammation.
http://www.jneuroinflammation.com/content/5/1/12/abstract
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=508269&contextCategoryId=40131
Medications Linked to Cognitive Decline More rapid rate of decline seen in seniors who start taking drugs with anticholinergic
activity
Beware of medications for
over active bladder, spastic colon and old fashion depression pills and old fashion antihistamines. All these medications
may make you become senile a little sooner.
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=510961&contextCategoryId=40131
Obese Mice Have Impaired Brain Insulin Transport
Reversed by starvation or triglycerides triolein
Again it
is worth while to loose weight and eat just enough to survive.
Insulin in the brain acts as a satiety factor, reduces appetite, and decreases body
mass.
Altered sensing by brain of insulin may be a leading
cause of weight gain and insulin
resistance. A decrease in the transport across the
blood-brain barrier (BBB) of insulin
may induce brain insulin resistance by
Results
from Largest Statin Study of Patients with Alzheimer’s Disease Show Lipitor® Has No Significant Impact on Disease
In an 18-month study of 640 patients, donepezil plus atorvastatin did not significantly affect cognition or global
function, compared with donepezil plus placebo.
http://www.pfizer.com/news/press_releases/pfizer_press_releases.jsp?rssUrl=http://mediaroom.pfizer.com/portal/site/pfizer/index.jsp?ndmViewId=news_view&ndmConfigId=1010794&newsId=20080416006472&newsLang=en
Glucose Monitoring
Not Productive
Conclusions In patients with newly diagnosed
type 2 diabetes self monitoring of blood glucose concentration has no effect on glycaemic control but is associated with higher scores on a
depression subscale.
Note: Stay away from high carbohydrate
diet, reduce your weight down to ideal weight and check Blood Hemoglobin A1C test every 3 months probably will be better.
http://www.bmj.com/cgi/content/full/bmj.39534.571644.BE
http://us.f812.mail.yahoo.com/ym/ShowLetter?MsgId=4209_4578375_36736_1980_10178_0_21237_48364_3163481768&Idx=1&YY=75051&y5beta=yes&y5beta=yes&inc=25&order=down&sort=date&pos=0&view=a&head=b&box=MEDICALNEWS408
Migraine Linked to Cardiovascular Disease Women with weekly migraines may be at increased risk of stroke
The data indicate that the association between migraine and CVD varies by migraine frequency.
While a J-shaped association was apparent for all ischemic events, women with a migraine frequency of at least weekly had
substantial increased risk of ischemic stroke.
http://www.abstracts2view.com/aan2008chicago/view.php?nu=AAN08L_S46.005
Can
statins reduce cancer risk?
The use of lipophilic statins
at sufficiently high dose might be associated with a clinically important reduction in the incidence of cancer. The American Journal of Medicine (4/2008)
Based on the evidence available, the pleiotropic effects of statins do not appear to reduce cardiovascular risk
more than would be predicted from LDL-C lowering alone. This study concluded that the focus should remain on closing the treatment
gap and improving adherence to therapies directed at lowering LDL-C and non-HDL cholesterol to reduce the burden of cardiovascular
disease. The American Journal of Cardiology (4/1)
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Another
heart disease predictor: Women are different
Di
DiDissatisfaction with sexual activity among women was modestly associated
with an increased prevalence of peripheral arterial disease but did not predict iniincident cardiovascular disease in comparison
with finfindings for men. Although this conclusion may represent insensitivity of the sexual satisfaction coinstruct to measure
female sexual dysfunction, it mimight also be due to physiological differences in sesexual functioning between men and women.
(Aaccompanied by a commentary) The American Journal of Medicine
(4/2008) |
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· St Diabetes increases heart attack, stroke risk
A new Danish study published in Circulation has shown that diabetes patients have more than 2.4 times the
reregular risk of dying from cardiovascular disease, apaproximately the same as individuals who have had a heheart attack.
One researcher encouraged early prprimary prevention of cardiovascular diseases for didiabetics. Reuters
(3/31) |
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Triglycerides May Explain Cognition Problems in ObesityObese mice performed more poorly in tests; triglyceride-lowering
drug improved performance
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=512530&contextCategoryId=40131
Relation
of the Metabolic Syndrome to Quantity of Coronary Atherosclerotic Plaque |
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In
conclusion, MS was independently associated with the presence and extent of both calcified and noncalcified coronary atherosclerotic
plaques detected using multidetector computed tomography. These data may explain the higher cardiovascular risk in these patients
and may lay the foundation for studies to determine whether such information may improve risk stratification. |
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The American Journal of Cardiology (4/15)
http://www.ajconline.org/article/S0002-9149(07)02474-5/fulltext
Cholesterol, Lifestyle Linked to Alzheimer's Disease
Patients
with elevated cholesterol levels in midlife are at increased risk of developing Alzheimer's disease, and patients with a history
of consuming more than two alcoholic beverages per day or smoking more than one pack of cigarettes per day are at increased
risk of developing earlier Alzheimer's disease.
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=510519&contextCategoryId=40131
More Arterial Disease When Vitamin D Levels
is low
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=510520&contextCategoryId=40130
Hypertension Linked to Mild Cognitive Impairment
Hypertension may increase risk of all-cause and non-amnestic mild cognitive impairment
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=510523&contextCategoryId=40130
Obesity, Inactivity Undermine Cancer Survivors' Prognosis
Cancer survivors in Canada
may be at higher risk from disease because they have low levels of physical activity and a high prevalence of obesity,
http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=511660&contextCategoryId=40130
